GEArray Q series Mouse Chemokines and Receptors Gene Array
Cat. No.
(Rad / Non-Rad)*
MM-005-02 / MM-005N-02
MM-005-04 / MM-005N-04
MM-005-12 / MM-005N-12
Kit Size
2 Arrays
4 Arrays
12 Arrays
Description
Each GEArray Q series Mouse Chemokines and Receptors Gene Array contains 67 chemokine and chemokine receptor
genes. The regulation of chemokine and chemokine receptor expression plays fundamental roles in the development,
homeostasis, and function of immune system. It is also evident they function in other cell types, such as endothelial cells
and cells of the nervous system. Through a simple side-by-side hybridization, you can determine the expression profile of
these chemokine and their receptor genes by using your experimental RNA samples and the array and reagents provided
in the kit.
Functional Gene Grouping
Small Inducible Cytokines:
Subfamily A (Cys-Cys): Scya1 (TCA3), Scya2 (JE), Scya3 (MIP-1α), Scya4 (MIP-1β), Scya5 (RANTES), Scya6 (C10),
Scya7 (MARC), Scya8 (MCP-2), Scya9 (MRP-2/ MIP-1r), Scya11 (eotaxin), Scya12 (mcp-5), Scya17 (TARC / ABCD-2),
Scya19 (MIP-3β/ ELC), Scya20 (MIP-3α/ LARC), Scya21a (6Ckine/ SLC/ exodus-2), Scya22 (MDC / ABCD-1) Scya24
(CCL24 / MPIF-2 / eotaxin-2), Scya25 (TECK), Scya27 (ALP / mILC), Scya28 (MEC/CCL28)
Subfamily B (Cys-X-Cys): Cxcl16 (SR-PSOX), Gro1, Scyb2 (MIP2), Scyb5 (LIX/GCP-2/ENA78), Scyb9 (Mig), Scyb10 (IP-
10), Scyb11, Scyb13 (BLC / angie2), Scyb14 (Kec/Bmac /MIP-2g), Scyb15
Other Subfamily Members: Scyc1 (Lptn / lymphotactin), Scyd1 (fractalkine / neurotactin)
Chemokine Receptors:
Blr1, Ccxcr1 (mXCR1), Cmkar3 (CXCR3), Cmkar4 (CXCR4), Cmkbr1 (CCR-1), Cmkbr1l1,
Cmkbr1l2, Cmkbr2, Cmkbr3, Cmkbr4, Cmkbr5, Cmkbr6 (CCR6), Cmkbr7 (EBI1), Cmkbr8 (CCR8), Cmkbr9 (GPR2),
Cmkbr10, Cmkor1, Cx3cr1, Cxcr6, D6-pending, IL8rb (Cmkar2), Ltb4r2, Pumag, Tapbp
Other Related Genes:
Dfy, Emap2, Epo, Ifna11, Ifnab, Pf4, Ppbp, Human PRL homolog, Sdf1, Sdf2, Tcp10
References
1.
2.
3.
4.
5.
Sallusto F, Mackay CR, Lanzavecchia A (2000) The Role Of Chemokine Receptors In Primary, Effector, And Memeory Immune Responses.
Annu. Rev. Immunol
18:
593-620.
Rossi D, Zlotnik A (2000) The Biology of Chemokines And Their Receptors.
Annu. Rev. Immunol
18:
217-242.
Zlotnik A, Yoshie O (2000) Chemokines: A New Classification System And Their Role In Immunity.
Immunity
12:
121-127.
Krishna Vaddi, Margaret Keller, Robert C. Newton, editors. (1997)
The Chemokine Facts Book
Academic Press.
James J Campbell and Eugene C Butcher (2000) Chemokines In Tissue-Specific And Microenvironment-Specific Lymphocyte Homing.
Current
Opinion in Immunology
12:336-341.
*
When ordering, please specify Rad or Non-rad, kit size and price.
Tel:
1.888.503.3187, 301.682.9200.
Fax:
1.888.465.9859, 301.682.7300.
Web:
www.superarray.com
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