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Cardiac arrest is the most serious sudden death disease. Once the patient develops the disease, he or she will be brain-dead in just 5 minutes. About 550,000 people die from cardiac arrest in China every year. The effective rescue time for cardiac arrest is only 4 minutes . The most effective treatment for sudden cardiac arrest is correct chest compressions and timely and accurate electrical defibrillation.
Cardiac arrest has gradually attracted the attention of the government. In recent years, many public places in our country have gradually been equipped with AEDs (automated external defibrillators). However, the success rate of cardiac arrest treatment in China is still less than 1%, which is far lower than the 30% success rate in developed countries. The reason is that the treatment of cardiac arrest is far from just being equipped with an electric defibrillator. The successful experience of developed countries comes from decades of cultivating national first aid knowledge and is difficult to apply to our country's national conditions. The contradiction between the time urgency of cardiac arrest treatment and the scarcity of emergency equipment and professionals has become a major problem in the current cardiac arrest treatment in China.
The emergency doctors we cooperate with have questioned the existing AEDs: existing AEDs and other emergency equipment have major flaws! The main flaws are as follows:
(1) Chest compression carries huge risks . It is extremely irresponsible to hand over chest compressions to someone without professional training . Wrong operation can be counterproductive and bear legal risks.
(2) The existing equipment is not easy to use . Existing defibrillation equipment often only has defibrillation function and is highly dangerous. Even our R&D personnel dare not use AED easily. During first aid, manual chest compressions and electric defibrillation need to be switched back and forth, which may injure the rescuer.
(3) ECG analysis is not intelligent . Existing equipment is limited to only carrying traditional algorithms, and the accuracy of ECG diagnosis is low, which greatly limits the success rate of treatment.
In order to solve the current difficulties faced by cardiac arrest treatment in our country and the shortcomings of existing equipment raised by doctors. As shown in Figure 1 , we designed an "intelligent chest compression and electric defibrillator all-in-one device".
Figure 1 Intelligent chest compression and defibrillation integrated device
This device is an integrated first aid device that does not require professional intervention . It integrates all the functions required for cardiac arrest first aid. Low risk, full functions, low cost, high intelligence, easy to use, easy to store and maintain . It can effectively solve the problems of high risk, cumbersome use, high cost, low intelligence and difficult maintenance of existing equipment .
This equipment independently and innovatively designed an rescue equipment that integrates a foldable ambulance stretcher, automatic ECG monitor, automatic ECG analyzer, full-chest automatic chest compression machine, and biphasic defibrillator. A huge improvement in "1+1>2 " .
The electric defibrillation circuit design of this device adopts a multi-isolation scheme . Compared with traditional non-isolated electric defibrillation circuits, it has the advantages of more stable operation and stronger anti-interference ability. At the same time, thanks to the adoption of a pure digital control scheme , it has the advantage of high control freedom.
This device integrates electric defibrillation and chest compression in its mechanical structure, which can save more than 30 seconds of rescue time. This is of great significance in the golden 4 minutes.
This device innovatively adopts the simultaneous transfer and full-function treatment solution, which is our first initiative. As shown in the animation 2 , it further improves the treatment efficiency.
Animation 2 Simultaneous transport and treatment (double-click to play)
2. Difficulties of the work
(1) This equipment independently developed and designed a special electric defibrillation circuit board based on national standards and complete machine requirements , as shown in Figure 3:
Figure 3 Self-designed special electric defibrillation circuit board
We also conducted various tests on the electric defibrillation circuit, as shown in Figure 4 and Figure 5. We used double eggs with an impedance close to the human chest as the experimental test load.
First, test the bioimpedance. The concave part of the lower waveform is the test waveform:
High voltage charging follows:
Animation 4 Quick charging 1KV (235J) energy
Discharge after full charge:
Animation 5: Release 100J defibrillation energy based on bioimpedance
The picture below is the waveform diagram of releasing 100J energy:
The picture below is the waveform diagram of releasing 200J energy:
(2) This design independently designed the chest compression power drive circuit, chest compression control circuit, ECG collection circuit, etc., and integrated them on the main board of the whole machine, as shown in Figure 6:
Figure 6 The complete motherboard
(3) This design independently developed and designed a set of automatic diagnosis programs, with a recognition rate far higher than that of commercial products, reaching over 99.7%. It is also supported by data from emergency departments of cooperative hospitals.
Figure 7 Confusion matrix of ECG signal classification results
(4) This design uses wavelet threshold denoising for ECG signal preprocessing. Compared with traditional algorithms, it has stronger performance and cleaner spectrum, which is beneficial to improving classification accuracy, as shown in Figure 8.
Figure 8 Wavelet denoising results
(5) This design follows national standards . For example, when defibrillation is not being performed or when the equipment accidentally loses power, it can automatically and quickly discharge the high-voltage electricity in the capacitor, and resume normal operation immediately after defibrillation, etc., in compliance with National safety standards.
The market potential of this product is huge. The United States is equipped with more than 350 AEDs for every 100,000 people, not including other rescue equipment, and China will reach this scale sooner or later. This year Beijing has required every school to be equipped with an AED.
Due to the government's current support for cardiac arrest treatment and the advantages of its own products, the potential market in China alone is as high as hundreds of billions, and large-scale deployment can save the government hundreds of billions of dollars.
This product effectively solves the problem of equipment fragmentation during cardiac arrest first aid, effectively solves the harm of AED to the personal safety of rescuers, and effectively solves the conflict between first aid and transport. It has great practical value. The prototype of this product has been developed. , there are currently a number of large-scale medical device manufacturers that have expressed intention to cooperate and have completed preliminary negotiations.
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